May 6, 2020

Sara Cascone

Research Fellow

in Eng4Life she is a member of the research and development team

telephone +39.089.964026

mail scascone@unisa.it

CV Full CV (request the password via email)

Academic Curriculum

Sara Cascone graduated, summa cum laude, in Chemical Engineering with a thesis in “Drug microencapsulation in biopolymers by ultrasound assisted atomization” in 2009. From 2009 to 2013 she has been student of doctoral course in Science and Technology for Chemical, Pharmaceutical, and Food Industry – Chemical Engineering course, gaining the Ph.D. degree in March 2013, defending a thesis in ”In silico and in vitro models in pharmacokinetic studies”.

Since 2013, she has stipulated, in the Department of Industrial Engineering, post-doc collaboration grants, one of them is still going on, on the research topic concerning the simulation of the gastrointestinal tract behavior. During these collaborations, she has been co-author of papers published in international journals and many publications on international conference proceedings. Her main research activities are the study of all the phenomena involved in the drug release after oral administration; the simulation of the mechanic, biochemistry, and mass transport of the gastrointestinal tract and their influence on drug release from tablets. Moreover, she studies the degradation kinetics (both enzymatic and not) of anesthetics, evaluating the effect of the operative parameters and of the enzymatic concentration on the drug degradation. Finally, she participates in the design and realization of a plant, firstly on a lab scale and then on industrial scale, to produce agricultural fertilizers constituted by chelated iron, after a process optimization. This activity has been in collaboration with an industrial partnership (Fertenia Srl).

Her didactic activities have been several seminars during the courses in “Release and directing of drugs” at the Department of Pharmacy, “Chemical Reactors”, “Chemical Reactors in the Food Industry”, and “Principles in Chemical Engineering” at the Department of Industrial Engineering. Since 2010 she has been part of the examination board in “Chemical Reactors in the Food Industry” and “Principles in Chemical Engineering” in the Chemical Engineering bachelor degree and “Transport Phenomena and Food Processes” in the Food Engineering master degree.

Theses

PhD thesis

  • Sara Cascone, In silico and in vitro models in pharmacokinetic studies (thesis extract PDF, full thesis PDF 4.1 MB), Tesi di Dottorato di Ricerca in Scienza e Tecnologie per l’Industria Chimica, Farmaceutica e Alimentare”, Chemical Engineering (XI Ciclo-Nuova Serie), Supervisors: Prof. Eng. Giuseppe Titomanlio, Prof. Eng. Gaetano Lamberti, Scientific Committee: Prof. Werner Weitschies, Prof. Iztok Grabnar

Master thesis

  • Sara Cascone, Microincapsulazione di farmaci in biopolimeri mediante atomizzazione assistita da ultrasuoni (thesis extract PDF, full thesis PDF 2.0 MB), Master Degree in Chemical Engineering, 20/11/2009, Supervisors: Prof. Eng. Giuseppe Titomanlio, Prof. Eng. Gaetano Lamberti

Bachelor thesis

  • Sara Cascone, Analisi delle cinetiche di idratazione e di rilascio di principi attivi da compresse di idrogeli (thesis extract PDF, full thesis PDF 1.1 MB), Bachelor Degree in Chemical Engineering, 27/09/2007, Supervisors: Prof. Eng. Giuseppe Titomanlio, Prof. Eng. Gaetano Lamberti (This thesis has been awarded as the best Italian Bachelor thesis in Chemical Engineering in 2007 by AIDIC-GRICU)

Publications